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Genetic Susceptibility Testing

Genetic Susceptibility Testing for Breast and Ovarian Cancer
by: Dr. Ronald Cypher

Advanced OB/GYN Associates offers genetic susceptibility testing for breast and ovarian cancers. Breast cancer will strike 180,000 women this year. In the general population, a woman has a 10 percent chance of developing breast cancer by the age of 80 and a 1.43 percent chance of developing ovarian cancer during her lifetime. However, when the cancer is caused by a specific mutation of certain genes, the chance for developing breast cancer jumps to 87 percent by age 70. The risk for ovarian cancer increases to 44-60 percent with a confirmed mutation.

The test examines two genes, BRCA1 and BRCA2, for very specific mutations. Having the mutations means that there is an increased risk for developing either type of cancer. Once our doctors are aware of the increased risk, they can use a more aggressive approach for early detection of cancer.

If you have a strong family history of breast or ovarian cancer and would like more information on BRCA1 and BRCA2 testing, please call the office at 285-9200.